Bioinformatics and drug discovery /

Bibliographic Details
Other Authors:	Larson, Richard S.
Format:	Book
Language:	English
Published:	Totowa, N.J. : Humana Press, [2006]
Series:	Methods in molecular biology ; v. 316.
Subjects:	Drug development. Bioinformatics. High throughput screening (Drug development) Combinatorial chemistry. Drug Design. Computational Biology > methods. Drug Evaluation, Preclinical. Genetic Techniques. Microarray Analysis. Pharmacogenetics > methods.

Table of Contents:

New strategies in drug discovery
Basic microarray analysis : strategies for successful experiments
From microarray to biological networks : analysis of gene expression profiles
Microarray analysis in drug discovery and clinical applications
Ontology-driven approaches to analyzing data in functional genomics
Gene evolution and drug discovery
Standardization of microarray and pharmacogenomics data
Clinical applications of bioinformatics, genomics, and pharmacogenomics
Protein interactions probed with mass spectrometry
Discovering new drug-targeting sites on flexible multidomain protein kinases : combining segmental isotopic and site-directed spin labeling for nuclear magnetic resonance dectection of interfacial clefts
Nuclear magnetic resonance-based screening methods for drug discovery
Receptor binding sites : bioinformatic approaches
In silico protein design : fitting sequence onto structure
Chemical database preparation for compound acquisition or virtual screening
Bioinformatics platform development : from gene to lead compound