http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
formulation and delivery in gene therapy, DNA vaccination and immunotherapy
xxii, 253 pages : illustrations (some color) ; 25 cm.
DNA vaccines - an overview -- DNA as a pharmaceutical - regulatory aspects -- From bulk to delivery : plasmid manufacturing and storage -- Minimized CpG-depleted, and methylated DNA vectors : towards perfection in nonviral gene therapy -- Localized nucleic acid delivery : a discussion of selected methods -- DNA needle injection -- Needleless jet injection of naked DNA for nonviral in vivo gene transfer -- Plasmid inhalation : delivery to the airways -- Hydrodynamic gene delivery -- DNA pharmaceuticals for skin diseases -- Electrotransfection - an overview -- Electrogenetransfer in clinical applications -- Cancer inhibition in mice after systemic application of plasmid-driven expression of small interfering RNAs
Includes bibliographical references and index.