The p53 tumor suppressor pathway and cancer /
| Other Authors: | |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
New York :
Springer,
[2005]
|
| Series: | Protein reviews ;
v. 2. |
| Subjects: |
Table of Contents:
- The p53 network
- The three-dimensional structure of p53
- Transcriptional activation by p53 : mechanisms and targeted genes
- Transcriptional repression by the p53 tumor suppressor protein
- Posttranslational modifications of p53 : upstream signaling pathways
- p53 in human cancer - somatic and inherited mutations and mutation-independent mechanisms
- MDM2 and MDMX regulators of p53 activity
- p53 family members : p63 and p73
- The oncogenic activity of p53 mutants
- Therapeutic strategies based on pharmacological modulation of p53 pathway