Apoptosis, genomic integrity, and cancer /

Bibliographic Details
Main Author: Van Lancker, Julien L., 1924-
Format: Book
Language:English
Published: Sudbury, Mass. : Jones and Bartlett Publishers, [2006]
Subjects:
Table of Contents:
  • Morphology and occurence of apoptosis
  • Recognition and disposal of the apoptotic bodies
  • Agents that trigger apoptosis
  • Genes and gene products in apoptosis of C. elegans
  • The Bcl-2 family
  • Interleukin 1-β converting enzyme (ICE) and caspases
  • The cytochrome c-dependent pathway to apoptosis
  • Inhibitor of apoptosis proteins (IAPs)
  • The p53 gene
  • Integrity of the genome and programmed cell death
  • Enzymes potentially involved in P53 activation
  • P53 and the cell cycle
  • Cell cycle checkpoints
  • Cell cycle arrest
  • P53 transactivation of GADD45 and MDM2
  • The P53 family and apoptosis
  • Tumor transforming growth factors and cancer
  • Protein tyrosine kinase receptors and cancer
  • The oncogenic GTPases
  • Non-receptor protein kinases and cancer
  • The PIK3/AkT pathway in cancer and apoptosis
  • Transcription factors and cancer
  • Cancer and genomic instability
  • Cancer and genomic instability : mismatch repair and cancer
  • Role and fanconi anemia, breast cancer and Bloom syndrome genes in oncogenesis
  • Cancer and apoptosis