http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
Apoptosis, genomic integrity, and cancer
xviii, 422 pages : illustrations ; 26 cm.
Morphology and occurence of apoptosis -- Recognition and disposal of the apoptotic bodies -- Agents that trigger apoptosis -- Genes and gene products in apoptosis of C. elegans -- The Bcl-2 family -- Interleukin 1-β converting enzyme (ICE) and caspases -- The cytochrome c-dependent pathway to apoptosis -- Inhibitor of apoptosis proteins (IAPs) -- The p53 gene -- Integrity of the genome and programmed cell death -- Enzymes potentially involved in P53 activation -- P53 and the cell cycle -- Cell cycle checkpoints -- Cell cycle arrest -- P53 transactivation of GADD45 and MDM2 -- The P53 family and apoptosis -- Tumor transforming growth factors and cancer -- Protein tyrosine kinase receptors and cancer -- The oncogenic GTPases -- Non-receptor protein kinases and cancer -- The PIK3/AkT pathway in cancer and apoptosis -- Transcription factors and cancer -- Cancer and genomic instability -- Cancer and genomic instability : mismatch repair and cancer -- Role and fanconi anemia, breast cancer and Bloom syndrome genes in oncogenesis -- Cancer and apoptosis
Includes bibliographical references and index.