Signalling pathways in acute oxygen sensing /

Bibliographic Details
Corporate Author: Novartis Foundation
Other Authors: Chadwick, Derek, Goode, Jamie
Format: Book
Language:English
Published: Chichester, UK ; Hoboken, NJ : John Wiley & Sons, [2006]
Series:Novartis Foundation symposium ; 272.
Subjects:
Table of Contents:
  • Chair's introduction
  • Regulation of gene expression by HIF-1
  • Regulation of HIF : prolyl hydroxylases
  • General discussion I
  • Regulation of HIF : asparaginyl hydroxylation
  • Oxygen - sensing by ion channels and mitochondrial function in carotid body glomus cells
  • The role of TASK-like K⁺ channels in oxygen sensing in the carotid body
  • Reactive oxygen species facilitate oxygen sensing
  • Oxygen sensing in neuroepithelial and adrenal chromaffin cells
  • Hypoxic regulation of Ca²⁺ signalling in astrocytes and endothelial cells
  • General discussion II
  • Functional proteeomics of BK potassium channels : defining the acute oxygen sensor
  • A central role for oxygen - sensitive K⁺ channels and mitochondria in the specialized oxygen - sensing system
  • Role for mitochondrial reactive oxygen species in hypoxic pulmonary vasoconstriction
  • Hypoxic pulmonary vasoconstriction - triggered by an increase in reactive oxygen species?
  • General discussion III
  • The role of twin pore domain and other K⁺ channels in hypoxic pulmonary vasoconstriction
  • AMP - activated protein kinase couples mitochondrial inhibition by hypoxia to cell-specific Ca²⁺ signalling mechanisms in oxygen - sensing cells
  • Role of capacitative Ca²⁺ entry byt not Na⁺/Ca²⁺ exchange in hypoxic pulmonary vasoconstriction in rat intrapulmonary arteries