Cell culture technology for pharmaceutical and cell-based therapies /

Bibliographic Details
Other Authors: Ozturk, Sadettin S., Hu, Wei-Shou, 1951-
Format: Book
Language:English
Published: New York : Taylor & Francis, 2006.
Series:Biotechnology and bioprocessing series ; 30.
Subjects:
Table of Contents:
  • Cell culture technology - an overview
  • Recombinant DNA technology and cell line development
  • Medium development
  • Cell metabolism
  • Protein glycosylation
  • Cell culture bioreactors
  • Aeration, mixing and hydrodynamics in bioreactors
  • Instrumentation and process control
  • Cell culture kinetics and modeling
  • Fed-batch cultivation of mammalian cells for the production of recombinant proteins
  • Optimization of high cell density perfusion bioreactors
  • Cell separation and product capture
  • Downstream processing
  • Formulation, filling and packaging
  • Validation of cell culture-based processes and qualification of associated equipment and facility
  • Facility design
  • Production of proteins by transient expression
  • Principles and applications of the insect cell-baculovirus expression vector system
  • Advances in adult stem cell culture
  • Ex vivo culture of hematopoietic and mesenchymal stem cells for tissue engineering and cell-based therapies