Cancer drug resistance /

Bibliographic Details
Other Authors: Teicher, Beverly A., 1952-
Format: Book
Language:English
Published: Totowa, N.J. : Humana Press, [2006]
Series:Cancer drug discovery and development.
Subjects:
Table of Contents:
  • The cycle between angiogenesis, perfusion, and hypoxia in tumors
  • Influence of tumor pH on therapeutic response
  • Tumor oxygenation and treatment response
  • Oncogenes and tumor suppressor genes in therapeutic resistance : the role of evolving interrelationships between cancer cells and host tissues
  • PET imaging of response and resistance to cancer therapy
  • Cancer stem cells : implications for development of more effective therapies
  • Therapeutic resistance in leukemia
  • Tumor site implantation and animal model selection in oncology
  • In vivo resistance
  • Characteristics of the metastatic phenotype : the melanoma experience
  • The microenvironment and drug resistance
  • Glutathione and glutathione S-transferases in drug resistance
  • Metallothioneins in drug resistance
  • Molecular determinants of intrinsic multidrug resistance in cancer cells and tumors
  • New and revised concepts in multidrug resistance : sestambi, SNPs, substrates, and stem cells
  • Cisplatin resistance : molecular basis of a multifaceted impediment
  • Regulation of the cellular pharmacology and cytotoxicity of cisplatin by copper transporters
  • Resistance to taxanes
  • CpG island methylation and drug resistance
  • De novo and acquired resistance to antitumor alkylating agents
  • Resistance to antiangiogenic agents
  • Resistance to antiestrogens
  • Mechanisms of glucocorticoid actions and resistance in multiple myeloma
  • Herceptin resistance
  • Role of TGF-beta in tumor progression and metastasis
  • p53-based immunotherapy of cancer
  • Response and resistance to ionizing radiation
  • Amplification in DNA copy numbers as a mechanism of acquired drug resistance
  • Cancer chemotherapy : clinical evidence for drug resistance
  • Molecular profiling in breast cancer : genomic approaches toward tailored cancer therapies
  • Tumor immune escape mechanisms