RNA towards medicine /
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
Berlin :
Springer,
2006.
|
| Series: | Handbook of experimental pharmacology.
v. 173. |
| Subjects: |
Table of Contents:
- Why RNA and DNA have different structures
- Regulatory RNAs as mediators of virulence gene expression in bacteria
- Regulatory RNAs in mammals
- Aminoglycoside interactions with RNAs and nucleases
- High-throughput RNA interference in functional genomics
- Antiviral applications of RNAi
- RNA interference : its use as antiviral therapy
- Gene silencing of virus replication by RNA interference
- Progress in the development of nucleic acid therapeutics
- Screening and determination of gene function using randomized ribozyme and siRNA libraries
- Ribozymes and siRNAs : from structure to preclinical applications
- Strategies to identify potential therapeutic target sites in RNA
- Oligonucleotide-based antiviral strategies
- Gene-expressed RNA as a therapeutic : issues to consider, using ribozymes and small hairpin RNA as specific examples
- RNA aptamers : from basic science towards therapy
- RNA aptamers directed against oligosaccharides
- Aptamer-based biosensors : biomedical applications
- Application of aptamers in therapeutics and for small-molecule detection
- RNA aptamers as potential pharmaceuticals against infections with African trypanosomes
- RNA targeting using peptide nucleic acid
- Locked nucleic acid : high-affinity targeting of complementary RNA for RNomics
- Engineering RNA-based circuits
- Selection of RNase-resistant RNAs