Molecular chaperones in health and disease /

Bibliographic Details
Other Authors: Alberti, S., Gaestel, Matthias
Format: Book
Language:English
Published: Berlin : Springer, [2006]
Series:Handbook of experimental pharmacology. v. 172.
Subjects:
Table of Contents:
  • Chaperones in preventing protein denaturation in living cells and protecting against cellular stress
  • Feedback regulation of the heat shock response
  • Protein folding in the endoplasmic reticulum and the unfolded protein response
  • Molecular chaperones in signal transduction
  • Chaperoning of glucocorticoid receptors
  • Heat shock response : lessons from mouse knockouts
  • HSFs in development
  • Heat shock proteins : endogenous modulators of apoptotic cell death
  • Protein aggregation as a cause for disease
  • The role of chaperones in Parkinson's disease and prion disease
  • Chaperoning oncogenes : Hsp90 as a target of geldanamycin
  • Heat shock proteins in immunity
  • Molecular chaperones and cancer immunotherapy
  • Hsp90 inhibitors in the clinic
  • Pharmacological targeting of catalyzed protein folding : the example of peptide bond cis/trans isomerases
  • Chemical chaperones : mechanisms of action and potential use
  • Pharmacological modulation of the heat shock response