Multiple sclerosis as a neuronal disease /

Bibliographic Details
Other Authors: Waxman, Stephen G.
Format: Book
Language:English
Published: Amsterdam ; Boston : Elsevier Academic Press, [2005]
Subjects:
Table of Contents:
  • The structure of myelinated axons in the CNS
  • Dialogues : communication between axons and myelinating glia
  • Molecular specializations at the glia-axon interface
  • Potassium channel organization of myelinated and demyelinated axons
  • The roles of potassium and calcium channels in physiology and pathophysiology of axons
  • The conduction properties of demyelinated and remyelinated axons
  • Altered distributions and functions of multiple sodium channel subtypes in multiple sclerosis and its models
  • Na⁺ channel reorganization in demyelinated axons
  • Ion currents and axonal oscillators : a possible biophysical basis for positive signs and symptoms in multiple sclerosis
  • Clinical pharmacology of abnormal potassium channel organization in demyelinated axons
  • Pathology of neurons in multiple sclerosis
  • Axonal degeneration in multiple sclerosis : the histopathological evidence
  • Natural history of multiple sclerosis : when do axons degenerate
  • Brain atrophy as a measure of neurodegeneration and neuroprotection
  • MRI-clinical correlations in multiple sclerosis : implications for our understanding of neuronal changes
  • Electrophysiological correlates of relapse, remission, persistent sensorimotor deficit and long-term recovery processes in multiple sclerosis
  • Inflammation and axon degeneration
  • Nitric oxide and axonal pathophysiology
  • Molecular mechanisms of calcium influx in axonal degeneration
  • Axonal damage and neuron death in multiple sclerosis and experimental autoimmune encephalomyelitis : the role of calpain
  • Mutations of myelination-associated genes that affect axonal integrity
  • Neuronal blocking factors in demyelinating diseases
  • Evidence for neuronal apoptosis in demyelinating CNS diseases
  • Mechanisms underlying Wallerian degeneration
  • AMAN : what it teaches us about mechanisms underlying axonal injury
  • Axonal degeneration as a predictor of outcome in neurological disorders
  • Remyelination as neuroprotection
  • Transplantation of peripheral-myelin-forming cells to repair demyelinated axons
  • Blocking the axonal injury cascade : neuroprotection in multiple sclerosis and its models
  • Functional brain reorganization and recovery after injury to white matter