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The G protein-coupled receptors handbook /

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Bibliographic Details
Other Authors: Devi, Lakshmi A.
Format: Book
Language:English
Published: Totowa, N.J. : Humana Press, [2005]
Series:Contemporary clinical neuroscience.
Subjects:
Carrier Proteins.
Handbook.
Table of Contents:
  • Structure-function relationships in G protein-coupled receptors : ligand bindng and receptor activation
  • Molecular mechanisms involved in the activation of rhodopsin-like seven-transmembrane receptors
  • GPCR folding and maturation : the effect of pharmacological chaperones
  • Regulated membrane trafficking and proteolysis of GPCRs
  • Heterotrimeric G proteins and their effector pathways
  • RGS proteins : orchestration of multiple signaling pathways
  • G protein- coupled receptor kinases
  • Regulators of GPCR activity : the arrestins
  • GPCR interacting proteins : classes, assembly, and functions
  • Biophysical and biochemical methods to study BPCR oligomerization
  • Oligomerization domains of G protein-coupled receptors : insights into the structural basis of GPCR association
  • Functional complementation and the analysis of GPCR dimerization
  • The role of oligomerization in G protein-coupled receptor maturation
  • Receptor oligomerization and trafficking
  • Modulation of receptor pharmacology by G protein-coupled receptor dimerization
  • Role of heteromeric GPCR interactions in pain/analgesia
  • Conformational plasticity of GPCR binding sites : structural basis for evolutionary diversity in ligand recognition
  • De-orphanizing GPCRs and drug development