Statistics in the pharmaceutical industry /

Bibliographic Details
Other Authors: Buncher, C. Ralph (Charles Ralph), 1938-, Tsay, Jia-Yeong, 1944-
Format: Book
Language:English
Published: Boca Raton, FL : Chapman & Hall/CRC Taylor & Francis Group, 2006.
Edition:Third edition.
Series:Biostatistics (New York, N.Y.)
Subjects:
Table of Contents:
  • Introduction to the evolution of pharmaceutical products
  • Statistical review and evaluation of animal carcinogenicity studies of pharmaceuticals
  • The FDA and the IND/NDA statistical review process
  • Clinical trial designs
  • Selecting patients for a clinical trial
  • Statistical aspects of cancer clinical trials
  • Recent statistical issues and developments in cancer clinical trials
  • Design and analysis of testosterone replacement therapy trials
  • Clinical trials of analgesic drugs
  • Statistical issues in HIV/AIDS research
  • The wonders of placebo
  • Active-controlled noninferiority/equivalence trials : methods and practice
  • Interim analysis and bias in clinical trials : the adaptive design perspective
  • Interim analysis and adaptive design in clinical trials
  • A regulatory perspective on data monitoring and interim analysis
  • Complex adaptive system, human health and drug response : statistical challenges in pharmacogenomics
  • Phase IV postmarketing studies
  • The role of contract research organizations in clinical research in the pharmaceutical industry
  • Global harmonization of drug development - a clinical statistics perspective
  • Bridging strategies in global drug development
  • Design and analysis strategies for clinical pharmacokinetic trials
  • Stability studies of pharmaceuticals
  • When and how to do multiple comparisons
  • Reference intervals (ranges) : distribution-free methods vs. normal theory