DNA damage recognition /

Bibliographic Details
Other Authors: Siede, Wolfram, Kow, Yoke Wah, Doetsch, Paul W.
Format: Book
Language:English
Published: New York : Taylor & Francis, 2006.
Subjects:
Table of Contents:
  • Dynamics of DNA damage recognition
  • In search of damaged bases
  • Increased specificity and effciency of base excision repair through complex formation
  • Structure and properties of DNA photoproducts
  • Damage recognition by DNA photolyases
  • Damage recognition by the bacterial nucleotide excision repair machinery
  • Recognition of DNA damage during eukaryotic nucleotide excision repair
  • Interactions of the transcription machinery with DNA damage in prokaryotes
  • DNA repair in actively transcribed genes in eukaryotic cells
  • Chromatin structure and the repair of UV light-induced DNA damage
  • The ultraviolet damage endonuclease (UVDE) protein and alternative excision repair : a highly diverse system for damage recognition and processing
  • Structural aspects of Pt-DNA adduct recognition by proteins
  • Structural aspects of polycyclic aromatic carcinogen-damaged DNA and its recognition by NER proteins
  • Structural features of DNA glycosylases and AP endonucleases
  • Repair of oxidized bases
  • Recognition of alkylating agent damage in DNA
  • Deaminated bases in DNA
  • New paradigms for DNA base excision repair in mammals
  • Recognition and repair of abasic sites
  • Oxidative mitochondrial DNA damage resistance and repair
  • Mechanism of DNA mismatch repair from bacteria to human
  • Interaction of the Escherichia coli Vsr with DNa and mismatch repair proteins
  • Mechanism of translesion DNA synthesis in Escherichia coli
  • Mechanism of bypass polymerases in eukaryotes
  • Structural features of bypass polymerases
  • Regulation of damage tolerance by the RAD6 pathway
  • Bochemical and cellular aspects of homologous recombination
  • The mechanism of vertebrate nonhomologous DNA end joining and its role in immune system gene rearrangements
  • Structural aspects of Ku and the DNA-dependent protein kinase complex
  • Cellular functions of mammalian DNA ligases
  • The Mre11/Rad50/Nbs1 complex
  • Histone γ-H2AX involvement in DNA double-strand break repair pathways
  • DNA strand-break recognition, signaling and resolution : the role of poly(ADP-ribose) polymerases-1 and -2
  • Cellular and molecular responses to alkylation damage in DNA
  • Damage signals triggering the Escherichia coli SOS response
  • Recognition of DNA damage as the initial step of eukaryotic checkpoint arrest
  • Responses to replication of DNA damage