Biomarkers in breast cancer : molecular diagnostics for predicting and monitoring therapeutic effect /

Bibliographic Details
Other Authors: Gasparini, Giampietro, Hayes, Daniel F., 1951-
Format: Book
Language:English
Published: Totowa, N.J. : Humana Press, [2006]
Series:Cancer drug discovery and development.
Subjects:
Table of Contents:
  • Guidelines for the design of clinical studies for the development and validation of therapeutically relevant biomarkers and biomarker-based classification systems
  • Analytical aspects of biomarker immunoassays in cancer research
  • Tissue microarrays : state-of-the-art, pitfalls, and promises
  • Gene expression profiling with DNA microarrays : revolutionary tools to help diagnosis, prognosis, treatment guidance, and drug discovery
  • Assays for gene amplification : state-of-the-art, pitfalls and promises
  • Cell kinetics
  • Urokinase-type plasminogen activator and PAI-1 : validated prognostic factors for breast cancer
  • Predictive value of c-erb-B2 for endocrine therapy and chemotherapy in breast cancer
  • erb-B2 as a therapeutic target
  • The epidermal growth factor receptor pathway as a selective molecular-targeted treatment in human breast cancer
  • p53 as a prognostic and predictive indicator
  • Predictive biomarkers in body fluids
  • Occult metastatic cells in breast cancer patients : state-of-the-art, pitfalls, and promises
  • Circulating HER2/neu : clinical utility
  • Circulating vascular endothelial growth factor : methods, prognostic significance, and potential application for antiangiogenic therapy
  • Detection of early tumor dissemination in patients with breast cancer
  • New technologies/new markers/new challenges