http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
xxi, 1176 pages : illustrations ; 25 cm.
sect. I. Basic principles -- Anatomy and physiology of the kidneys -- Molecular and cell biology of normal and diseased or intoxicated kidney -- Assessing renal effects on toxicants in vivo -- In vitro techniques in screening and mechanistic studies : organ perfusion, slices and nephron components -- In vitro techniques in screening and mechanistic studies : cell culture, cell-free systems, and molecular and cell biology -- sect. II. Mechanisms of nephrotoxicity -- Role of xenobiotic metabolism -- Mechanisms of renal cell death -- Signal transduction in renal cell repair and regeneration -- Chemical-induced nephrocarcinogenicity in the Eker rat : a model of chemical-induced renal carcinogenesis -- The role of endocytosis in nephrotoxicity -- Role of cellular energetics in nephrotoxicity -- Adhesion molecules in renal physiology and pathology -- Oxidant mechanisms in toxic acute renal failure -- sect. III. Clinical nephrotoxicity and specific classes of nephrotoxicants -- Vasoactive and inflammatory substances -- Analgesic nephropathy -- Antibiotic-induced nephrotoxicity -- Nephrotoxicity of cyclosporine and other immunosuppressive and immunotherapeutic agents -- Cisplatin-induced nephrotoxicity -- The pathogenesis and prevention of radiocontrast medium induced renal dysfunction -- Analgesics and non-steroidal anti-inflammatory drugs -- Mycotoxins affecting the kidney -- Nephrotoxicology of metals -- Chemical-induced nephrotoxicity mediated by glutathione S-conjugate formation -- sect. IV. Risk and safety assesment -- The role of epidemiology in human nephrotoxicity -- Age, sex and species differences in nephrotoxic response -- Risk assessment of nephrotoxic metals -- Risk assessment for selected therapeutics
edited by Joan B. Tarloff and Lawrence H. Lash.
Previous edition: New York: Raven, 1993.