Pharmacogenomics : methods and protocols /

Bibliographic Details
Other Authors: Innocenti, Federico
Format: Book
Language:English
Published: Totowa, N.J. : Humana Press, [2005]
Series:Methods in molecular biology (Clifton, N.J.) ; v. 311.
Subjects:
Table of Contents:
  • Pharmacogenomics : historical perspective and current status
  • Transfection assays with allele-specific constructs : functional analysis of UDP-glucuronosyltransferase variants
  • Snapshot of the allele-specific variation in human gene expression
  • Genome-wide analysis of allele-specific gene expression using oligo microarrays
  • HaploChIP : an in vivo assay
  • Aspects influencing genotyping method selection
  • Denaturing high-performance liquid chromatography for mutation detection and genotyping
  • Pyrosequencing of clinically relevant polymorphisms
  • Kinetic fluorescence-quenching detection assay for allele frequency estimation
  • Matrix-assisted laser desorption/ionization time of flight mass spectrometry
  • Fluorescence-based fragment size analysis
  • Single-nucleotide polymorphism genotyping in DNA pools
  • TaqMan genotyping of insertion/deletion polymorphisms
  • PharmGKB : the pharmacogenetics and pharmacogenomics knowledge base
  • Systems for the management of pharmacogenomic information