Ion channels in the pulmonary vasculature /

Bibliographic Details
Other Authors: Yuan, Jason X.-J., 1963-
Format: Book
Language:English
Published: Boca Raton : Taylor & Francis, 2005.
Series:Lung biology in health and disease ; v. 197.
Subjects:
Table of Contents:
  • Membrane electrical properties of vascular smooth muscle cells of the pulmonary circulation
  • Excitation-contraction coupling in the pulmonary vasculature
  • Ion channel heterogeneity in the pulmonary vascular bed : a basis for site-specific responses to vasoactive stimuli
  • Voltage-gated Ca²⁺ channels in the pulmonary vasculature
  • Receptor-operated Ca²⁺ channels
  • Transient receptor potential cation channels and store-operated Ca²⁺ channels
  • Ca²⁺ releasing channels in pulmonary vascular smooth muscle cells
  • Agonist-mediated regulation of Ca²⁺ transients in PASMC's
  • Epithelial sodium channel function in health and disease in the adult lung
  • Voltage-dependent Na⁺ channels in pulmonary vascular smooth muscle cells
  • Voltage-gated potassium channels in pulmonary artery smooth muscle cells
  • Ca²⁺-activated, voltage-dependent K⁺ channels
  • ATP-sensitive and inward rectifier K⁺ channels
  • 2P domain K⁺ channels and their role in chemoreception
  • Ca²⁺-activated CI⁻channels and pulmonary vascular tone
  • Volume-sensitive CI⁻channels in pulmonary vascular smooth muscle and endothelial cells
  • Molecular physiology of O₂₋sensitive ion channels
  • Hypoxia-induced modulation of O₂₋sensitive K⁺ channels in pulmonary vascular smooth muscle cells
  • Ion channels and the effects of hypoxia in pulmonary artery endothelial cells
  • Aquaporins in the vasculature
  • Functional roles of ion channels in the regulation of membrane potential and pulmonary vascular tone
  • Calcium channels, calcium signaling, and lung vascular barrier regulation
  • Role of Ca²⁺ sparks in the regulation of pulmonary vascular tone
  • Ion channels and hypoxic pulmonary vasoconstriction
  • Essential role of anion channels in induction of apoptotic and necrotic cell death
  • Downregulated Kv channels and upregulated TRPC channels in primary pulmonary hypertension
  • Developmental regulation of ion channel function and expression in the pulmonary vasculature
  • Anorexigens and pulmonary arterial hypertension : the role of potassium channels
  • Isolation and culture of pulmonary artery smooth muscle cells
  • Measurement of ion channel function using conventional patch-clamp techniques
  • Planar electrodes : the future of voltage clamp
  • Correlation of ion channel activity with gene expression using single-cell RT-PCR and patch-clamp techniques
  • Ion channel trafficking
  • Functional study of cloned ion channels in mammalian transfection systems using site-directed mutagenesis
  • Screening for mRNA expression using the polymerase chain reaction
  • Practical aspects of confocal imaging of Ca²⁺ sparks and cytoplasmic Ca²⁺ concentration
  • Use of transgenic and gene-targeted mice to study ion channel function in the pulmonary vasculature