Genetics of autoimmunity /

Bibliographic Details
Corporate Author: Symposium on Genomics of Autoimmunity
Other Authors: Bock, Gregory, Goode, Jamie
Format: Conference Proceeding Book
Language:English
Published: Chichester, UK ; Hoboken, NJ : John Wiley & Sons, 2005.
Series:Novartis Foundation symposium ; 267.
Subjects:
Table of Contents:
  • Chair's introduction
  • Patterns of genetic variation in humans and mice
  • Haplotype tagging in pharmacogenetics
  • Multiple sclerosis : a haplotype association study
  • Mapping genes for asthma and psoriasis
  • Natural genetic variants influencing type 1 diabetes in humans and in the NOD mouse
  • The importance of epistatic interactions in the development of autoimmunity
  • Mapping autoimmune disease genes in humans : lessons from IBD and SLE
  • A combined genetics and genomics approach to unravelling molecular pathways in coeliac disease
  • Progress towards understanding the genetic pathogenesis of systemic lupus erythematosus
  • A molecular dissection of lymphocyte unresponsiveness induced by sustained calcium signalling
  • Genetic lesions in thymic T cell clonal deletion and thresholds for autoimmunity
  • An autoimmune disease-associated CTLA4 splice variant lacking the B7 binding domain signals negatively in Tcells
  • Large-scale screens for cDNAs with in vivo activity
  • Genomic mining of new genes and pathways in innate and adaptive immunity