Syndromes of hormone resistance on the hypothalamic-pituitary-thyroid axis /

Bibliographic Details
Other Authors: Beck-Peccoz, P.
Format: Book
Language:English
Published: Boston : Kluwer Academic Publishers, [2004]
Series:Endocrine updates ; 22.
Subjects:
Table of Contents:
  • Molecular basis of thyroid hormone action
  • Tissues specific action of thyroid hormones : insights of knock out animal models
  • Learning from nature's experiments on the thyroid hormone receptor; X-ray structures of RTH mutant ligand-binding domains
  • Molecular pathogenesis of resistance to thyroid hormone
  • Syndromes of resistance to thyroid hormone : clinical aspects
  • Resistance to thyroid hormone in the absence of mutations in the thyroid hormone receptor genes
  • Lessons learned from TR-beta mutant mice
  • Towards the rational design of hormone analogs which complement receptor mutations
  • Multi-factorial regulation of in vivo action of TR-beta mutants - lessons learned from RTH mice with a targeted mutation in the TR-beta gene
  • The effect of vitamin A, retinoids and retinoid receptors on the hypothalamic-pituitary-thyroid axis
  • Pituitary resistance to thyroxine action due to a defect in the type 2 deiodinase
  • Different forms of resistance to thyrotropin (TSH)