Restriction endonucleases /

Bibliographic Details
Other Authors: Pingoud, A. (Alfred)
Format: Book
Language:English
Published: Berlin ; New York : Springer, [2004]
Series:Nucleic acids and molecular biology. 14.
Subjects:
Table of Contents:
  • A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes
  • Restriction-modification systems as minimal forms of life
  • Molecular phylogenetics of restriction endonucleases
  • Sliding or hopping ? How restriction enzymes find their way on DNA
  • The type I and III restriction endonucleases : structural elements in molecular motors that process DNA
  • The integratoin of recognition and cleavage : x-ray structures of pre-transition state complex, post-reactive complex and the DNA-free endonuclease
  • Structure and function of EcoRV endonuclease
  • Two of a kind : BamHI and Bg1II
  • Structure and function of the tetrameric restriction enzymes
  • Structure and function of type IIE restriction endonucleases - or : from a plasmid that restricts phage replication to a new molecular DNA recognition mechanism
  • Analysis of type II restriction endonucleases that interact with two recognition sites
  • The role of water in the EcoRI-DNA binding
  • Role of metal ions in promoting DNA binding and cleavage by restriction endonucleases
  • Restriction endocucleases : structure of the conserved catalytic core and the role of metal ions in DNA cleavage
  • Protein engineering of restriction enzymes
  • Engineering and applications of chimeric nucleases