The human genome : a user's guide /
| Main Author: | |
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| Other Authors: | |
| Format: | Book |
| Language: | English |
| Published: |
Amsterdam ; Boston, M.A. :
Elsevier Academic Press,
[2005]
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| Edition: | Second edition. |
| Subjects: |
Table of Contents:
- Sec. 1. The basics of heredity
- Slaying molecular dragons : Brenda's tale
- The answer in a nutshell : genes, proteins and the basis of life
- Mendel and the concept of the gene
- Human Mendelian genetics
- One man's trait is another man's disease
- Sec. 2. The central dogma of molecular biology
- DNA : the genetic alphabet
- The central dogma of molecular biology : how genes encode proteins
- Splicing the modular gene
- Orchestrating the human genome
- Sec. 3. How chromosomes move
- So what are chromosomes anyway?
- How cells move your genes around
- Passing genes between generations
- The chromosomal basis of heredity
- Sec. 4. Mutation
- Absent essentials and monkey wrenches
- How we detect mutation
- We are all mutants
- What constitutes normal?
- Mutations in mammoth genes
- Expanded repeat traits
- Sec. 5. Genes, chromosomes, and sex
- The X and Y chromosomes : the odd couple
- Genetics of sex, gender, and orientation
- Aneuploidy : when too much or too little counts
- Sec. 6. Breaking the rules
- Imprinting
- Imitating heredity : one trait, many causes
- Sec. 7. The human genome landscape
- The human genome project
- There's cloning and then there's cloning
- The human genome sequence
- Finding genes in the human genome
- Sec. 7. Complex and heterogeneous traits
- Genotype phenotype correlations
- How complex can it get?
- Quantitative traits
- The MAOA gene : is there a genetic basis for criminality?
- The multiple-hit hypothesis : the genetics of cancer
- Sec. 9. Genetic testing and therapy
- Genetic testing and screening
- Magic bullets : the potential for gene therapy
- Sec. 10. Fears, faith, and fantasies
- Heroes among us
- Fears, faith, and fantasies