Polymeric gene delivery : principles and applications /

Bibliographic Details
Other Authors: Amiji, Mansoor M.
Format: Book
Language:English
Published: Boca Raton, Fla. : CRC Press, [2005]
Subjects:
Table of Contents:
  • Pt. I. Gene delivery : challenges and opportunities
  • Tissue- and cell-specific targeting for the delivery of genetic information
  • Biological barriers to gene transfer
  • Cellular uptake and trafficking
  • Pharmacokinetics of polymer-plasmid DNA complex
  • Pt. II. Condensing polymeric systems
  • Poly(L-lysine) and copolymers for gene delivery
  • Gene delivery using polyethylenimine and copolymers
  • Poly(2-(dimethylamino)ethyl methacrylate)-based polymers for the delivery of genes in vitro and in vivo
  • Cationic dendrimers as gene transfection vectors : dendri-poly(amidoamines) and dendri-poly(propylenimines)
  • Poly(ethylene glycol)-conjugated cationic dendrimers
  • Water-soluble lipopolymers for gene delivery
  • Cyclodextrin-containing polymers for gene delivery
  • Gene delivery using polyimidazoles and related polymers
  • Degradable poly(beta-amino ester)s for gene delivery
  • Cationic polyesters as biodegradeable polymeric gene delivery carriers
  • Poly(aminoamine)s for gene delivery
  • Cationic polysaccharides for gene delivery
  • Gene delivery using chitosan and chitosan derivatives
  • Pt. III. Non-condensing polymeric systems
  • Pluronic® block copolymers for nonviral gene delivery
  • Use of poly(N-vinyl pyrrolidone) with noncodensed plasmid DNA formulations for gene therapy and vaccines
  • Use of HPMA copolymers in gene delivery
  • Pt. IV. Polymeric nanospheres and microspheres
  • Biodegradable nanoparticles as a gene expression vector
  • Nanoparticles made of poly(lactic acid) and poly(ethylene oxide) as carriers of plasmid DNA
  • Poly(alkylcyanoacrylate) nanoparticles for nucleic acid delivery
  • Layer-by-layer nanoengineering with polyelectrolytes for delivery of bioactive materials
  • Ex vivo and in vivo adenovirus-mediated gene delivery in refactory cells via nanoparticle hydrogel formulation
  • Protein nanoparticles for gene delivery
  • Gene delivery using poly(lactide-co-glycolide) microspheres
  • Polyanhydride microspheres for gene delivery
  • Microspheres formulated from native hyaluronan for applications in gene therapy
  • Pt. V. Specialized delivery systems
  • Genetically engineered protein-based polymers : potential in gene delivery
  • Glycopolymer tools for studying targeted nonviral gene delivery
  • Targeted gene delivery via the folate receptor
  • Transferrin receptor-targeted gene delivery systems
  • Gene delivery to the lungs
  • Cutaneous gene delivery
  • Enhancement of wound repair by sustained gene transfer via hyaluronan matrices
  • Gene delivery from tissue engineering matrices
  • Gene therapy stents for in-stent restenosis
  • Gene delivery using bioMEMs