DNA methylation : approaches, methods, and applications /

Bibliographic Details
Other Authors: Esteller, Manel
Format: Book
Language:English
Published: Boca Raton : CRC Press, [2005]
Subjects:
Table of Contents:
  • Impact of DNA methylation on health and disease
  • Uses of DNA methylation in cancer diagnosis and risk assessment
  • DNA methylation in X inactivation, imprinting, and associated diseases
  • Studying mammalian DNA methylation : bisulfite modification
  • Bisulfite PCR-based techniques for the study of DNA methylation
  • Microarray analysis of DNA methylation targets identified by methyl-CpG-binding proteins
  • Arbitrarily primed-PCR and related DNA methylation methodologies
  • Discovering DNA methylation differences with restriction landmark genomic scanning
  • Quantitative determination of 5-methylcytosine DNA content : HPCE and HPLC
  • Qualitative determination of 5-methylcytosine and other components of the DNA methylation machinery : immunofluorescence and chromatin immunoprecipitation
  • Mouse models for the study of DNA methylation
  • DNA demethylating agents : concepts
  • DNA demethylating agents : preclinical evaluation as anticancer agents
  • DNA demethylating agents : clinical uses