Transcription factors /

Bibliographic Details
Other Authors: Akira, S., Gossen, Manfred, Kaufmann, Jörg, Triezenberg, Steven J.
Format: Book
Language:English
Published: Berlin : Springer, [2004]
Series:Handbook of experimental pharmacology ; v. 166.
Subjects:
Table of Contents:
  • Pt. 1. An introduction to transcription factors
  • Mechanisms of transcriptional activation in eukaryotes
  • Multiple mechanisms of transcriptional repression in eukaryotes
  • genomic approaches to the study of transcription factors
  • Pt. 2. Transcription factors in pathophysiology
  • Biological roles of the STAT family in cytokine signaling
  • Members of the T-cell factor family of DNA-binding proteins and their roles in tumorigenesis
  • Transcription factors in the control of tumor development and progression by TGF-β signaling
  • The p⁵³ transcription factor as therapeutic target in cancer
  • The Role of Ets transcription factors in mediating cellular transformation
  • Function of the E2F transcription factor family during normal and pathological growth
  • c-Myc in cellular transformation and cancer
  • NF-kB : critical regulator of inflammation and the immune response
  • Hepatitis B virus X protein : structure-function relationships and role in viral pathogenesis
  • Regulation of xenobiotic detoxification by PXR, CAR, GR, VDR and SHP receptors : consequences in physiology
  • Pt. 3. Exogenous control of transcription factor activity
  • Potential of transcription factor decoy oligonucleotides as therapeutic approach
  • Selective estrogen receptor modulators as therapeutic agents in breast cancer treatment
  • Artificial zinc finger peptides : a promising tool in biotechnology and medicine
  • Tetracycline-controlled transactivators and their potential use in gene therapy applications
  • Modulating transcription with artificial regulators