Stem cells in development and disease /
| Other Authors: | |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Amsterdam :
Boston : Elsevier Academic Press,
[2004]
|
| Series: | Current topics in developmental biology ;
v. 60. |
| Subjects: |
Table of Contents:
- Therapeutic cloning and tissue engineering
- Principles of tissue engineering
- Stem cells
- Therapeutic cloning
- Applications of tissue engineering and therapeutic cloning
- α-synuclein : normal function and role in neurodegenerative disease
- Introduction to the synuclein protein family
- Synuclein in synaptic development and maintenance
- Synuclein protein interactions
- Synucleinopathies
- Structural properties of a α-synuclein protein
- Implications of oxidative and nitrative injury in synucleinopathies
- Effects of oxidation and nitration on α-synuclein fibril formation
- Possible role of pesticides and other toxic chemicals in PD
- Transgenic and nontransgenic animal models of synucleinopathies
- Structure and function of eukaryotic DNA methyltransferases
- DNA methylation : a heritable epigenetic mark
- Eukaryotic DNA methyltransferases
- Function of DNA methylation
- Mechanical signals as regulators of stem cell fate
- Mechanical regulation of limb development
- Theoretical models of mechanical stress in development
- In vivo experimentation
- In vitro experimentation
- Origins of mammalian hematopoiesis : in vivo paradigms and in vitro models
- Introduction : the hematopoietic system
- Hematopoiesis : de muibus et maribus
- Points of divergence between murine and human blood formation
- Hematopoiesis from embryonic stem cells
- What remains to be learned?
- Regulation of gene activity and repression : a consideration of unifying themes
- Regulation of imprinted gene activity and repression
- A consideration of recurrent themes
- Molecular basis for the chloride channel activity of cystic fibrosis transmembrane conductance regulator and the consequences of disease-causing mutations
- Role of cystic fibrosis transmembrane conductance regulator (CFTR) channel function in tissue physiology and pathophysiology
- Cell biology of CFTR and the major CF mutant (delta F508)
- Quanternary structure of CFTR
- The permeation pore of CFTR
- Molecular basis for regulation by phosphorylation
- Molecular basis for regulation by nucleotides
- Future directions