Protein NMR techniques /

Bibliographic Details
Other Authors: Downing, A. Kristina (Anna Kristina)
Format: Book
Language:English
Published: Totowa, N.J. : Humana Press, [2004]
Edition:Second edition.
Series:Methods in molecular biology (Clifton, N.J.) ; v. 278.
Subjects:
Table of Contents:
  • Screening and optimizing protein production in E. coli
  • Isotopic labelling of recombinant proteins from the methylotrophic yeast Pichia pastoris
  • Perdeuteration/site-specific protonation approaches for high moleculae weight proteins
  • Segmental isotopic labelling for structural biological applications of NMR
  • TROSY-based correlation and NOE spectroscopy for NMR structural studies of large proteins
  • Media for studies of partially aligned states
  • Residual dipolar couplings in protein structure determination
  • Projection angle restraints for studying structure and dynamics of biomolecules
  • Characterizing domain interfaces by NMR
  • Characterization of the overall rotational diffusion of a protein from 15N relaxation measurements and hydrodynamic calculations
  • TROSY-based NMR experiments for the study of macromolecular dynamics and hydrogen bonding
  • Measurement of intermediate exchange phenomena
  • NMR studies of partially folded molten globule states
  • Structure determination of protein complexes by NMR
  • NMR studies of protein/nucleic acid interactions
  • Using NMRView to visualize and analyze the NMR spectra of macromolecules
  • Automated NMR structure calculation with CYANA
  • NOE assignment with ARIA 2.0: the nuts and bolts
  • Membrane protein structure determinations using solid state NMR