Pneumocystis pneumonia.

Bibliographic Details
Other Authors: Walzer, Peter D., 1942-, Cushion, Melanie
Format: Book
Language:English
Published: New York : Marcel Dekker, [2005]
Edition:Third edition, revised and expanded /
Series:Lung biology in health and disease ; 194.
Subjects:
Table of Contents:
  • Pt. One. The organism
  • Historical overview
  • Nomenclature and genetic variation of Pneumocystis
  • Pneumocystis cellular structure
  • Surface antigens
  • Signal transuction and cellular communication
  • Transmission and epidemiology
  • Pneumocystis genome project and genomic organization
  • Pt. Two. Host defenses/interactions with the host
  • The neonatal period
  • Interactions of Pneumocystis with alveolar macrophages and epithelial cells
  • T cells in defense against pneumocystis
  • Cytokines
  • The role of humoral immunity in the defense against Pneumocystis
  • The pulmonary surfactant system in Pneumocystis pneumonia
  • Mechanisms of lung injury during Pneumocystis pneumonia
  • Pt. Three. Infection in humans
  • Clinical presentation and diagnosis of Pneumocystis pneumonia in HIV-infected patients
  • Pneumocystis pneumonitis in non-HIV-infected patients : update
  • Pneumocystis jirovecii pneumonia in AIDS patients in the developing world
  • Immunological features of Pneumocystis infection in humans
  • Molecular typing and epidemiological insights
  • Current regimens for treatment and prophylaxis of Pneumocystis jirovecii pneumonia
  • Lipids
  • Polyamines, iron and Pneumocystis carinii
  • DHFR and IMPDH : enzymes exploitable as drug targets in Pneumocystis
  • Dihydropteroate synthase and cytochrome B : the problem of emerging resistance
  • Development of candidate anti-Pneumocystis drugs : in vitro and in vivo approaches