Molecular neurobiology of Alzheimer disease and related disorders /

Bibliographic Details
Other Authors: Takeda, Masatoshi, 1949-, Tanaka, Toshihisa, Cacabelos, R. (Ramon)
Format: Book
Language:English
Published: Basel ; New York : Karger, [2004]
Subjects:
Table of Contents:
  • Methods of regulating Alzheimer pathogenesis : diet, oxidative damage and inflammation
  • The RNA-binding protein causes aberrant splicing of presenilin-2 pre-mRNA in sporadic Alzheimer's disease
  • Alzheimer's gamma-secretase mechanism produces amyloid-beta-protein like peptides simultaneously with release of intracellular signaling fragments
  • Pivotal role of neurofibrillary degeneration in Alzheimer disease and therapeutic targets
  • Tau pathology of sporadic tauopathies
  • Deregulation of GSK-3beta and JNK in a mouse model of tauopathy : a kinase combination that induces Alzheimer-type tau hyperphosphorylation
  • Clinical assessment of the genetic risk functions in Alzheimer's disease
  • Hydrogen sulfide is severely decreased in Alzheimer disease brains
  • Functional analysis of the presenilin complex and gamma-secretase activity
  • Pharmacogenomic studies with a combination therapy in Alzheimer's disease
  • Nicotinic receptor stimulation blocks neurotoxicity induced by amyloid-beta via the phosphatidylinositol-3-kinase cascade
  • Involvement of unfolded protein response in Alzheimer's disease
  • Advances in the development of biomarkers for Alzheimer's disease - From CSF total tau and amyloid-beta(1-42) proteins to phosphorylated tau and amyloid-beta-antibodies
  • Genetic analysis of familial Alzheimer's disease in a Japanese population
  • Oxidative stress in Alzheimer disease : the earliest cytological and biochemical feature
  • Neurogenesis : a promising therapeutic target for Alzheimer disease and related disorders
  • Learning deficits in N279K tau transgenic mice and an assembly model of tau protein
  • Animal models of tauopathies
  • Aberrant splicing of tau transcripts in frontotemporal dementia with Parkinsonism linked to chromosome 17
  • Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau
  • Activated protein kinases and phosphorylated tau protein in Alzheimer disease
  • A functional genomics approach to the analysis of biological markers in Alzheimer disease