Genomic and molecular neuro-oncology /

Bibliographic Details
Other Authors: Zhang, Wei, 1963 October 9-, Fuller, Gregory N.
Format: Book
Language:English
Published: Sudbury, Mass. : Jones and Bartlett Publishers, [2004]
Subjects:
Table of Contents:
  • pt. I. Genomic and genetic alterations in gliomas
  • Methylation and genomic damage in gliomas
  • Molecular and clinical aspects of 1p/19q loss in oligodendroglioma
  • Functional inactivation of p53 in gliomas
  • PTEN, a tumor suppressor gene frequently mutated in glioblastomas
  • Molecular genetics of the SWI/SNF family gene INI1 in atypical teratoid/rhabdoid tumors
  • pt. II. Molecular alterations in gliomas
  • Molecular markers of gilomas
  • Molecular and biological determinants of invasiveness and angiogenesis in central nervous system tumors
  • Insulin-like growth factors and insulin-like growth factor binding proteins in CNS tumors
  • pt. III. Genomics and informatics
  • Glioma transcriptomes : classifiers and classification
  • Tissue microarrays : applications in neuro-oncology research
  • Abnormal regulation of RNA splicing in gilomas
  • Chromosomal imbalances in oligodendroglial tumors as detected by comparative genomic hybridization
  • Statistical considerations in the design and analysis of microarray experiments
  • Transcriptome-based glioma classification using informative gene set
  • pt. IV. Animal models
  • Mouse models for infiltrative gliomas
  • Dissecting gliomagenesis using glial-specific transgenic mouse models
  • pt. V. Molecular therapeutics
  • Gene-based therapy for gliomas : targeting the cancer genomes
  • Therapeutic targeting of the molecular pathways that induce brain tumor development