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Advances in Down syndrome research /

Animal models.

Bibliographic Details
Other Authors: Lubec, Gert
Format: Book
Language:English
Published: Wien ; New York : Springer, 2003.
Series:Journal of neural transmission. Supplementum ; 67.
Subjects:
Down syndrome.
Table of Contents:
  • A new mouse model for Down Syndrome
  • Predicting pathway perturbations in Down Syndrome
  • Aberrant protein expresssion of transcription factors BACH1 and ERG, both encoded on chromosome 21, in brains of patients with Down Syndrome and Alzheimer's disease
  • Cell cycle and cell size regulation in Down Syndrome cells
  • Transcription factor REST dependent proteins are comparable between Down syndrome and control brains: challenging a hypothesis
  • An altered antioxidant balance occurs in down Syndrome fetal organs : implications for the "gene dosage effect" hypothesis
  • Overexpression of C1-tetrahydrofolate synthase in fetal Down Syndrome brain
  • Increased expression of human reduced folate carrier in fetal Down Syndrome brain
  • Chromosome 21 KIR channels in brain development
  • Reduction of chromatin assembly factor 1 p60 and C21orf2 protein, encoded on chromosome 21, in Down Syndrome brain
  • The MNB/DYRK1A protein kinase : neurobiological functions and Down Syndrome implications
  • The MNB/DYRK1A protein kinase : genetic and biochemical properties
  • Cytoskeleton derangement in brain of patients with Down Syndrome, Alzheimer's disease and Pick's disease
  • The cerebral cortex in Fetal Down Syndrome
  • Polysomnography in transgenic hSOD1 mice as Down Syndrome model
  • Spectrum of cognitive, behavioural and emotional problems in children and young adults with Down Syndrome
  • Overexpression of transcription factor BACH1 in Fetal Down Syndrome brain
  • Down Syndrome and associated congenital malformations
  • RNA microarray analysis of channels and transporters in normal and Fetal Down Syndrome (trisomy 21) brain
  • Heart type fatty acid binding protein (H-FABP) is decreased in brains of patients with Down Syndrome and Alzheimer's disease
  • Stem cell marker expression in human trisomy 21 amniotic fluid cells and trophoblasts