Molecular diagnosis of genetic diseases /

Bibliographic Details
Other Authors: Elles, Rob, Mountford, Roger
Format: Book
Language:English
Published: Totowa, NJ : Humana Press, [2004]
Edition:Second edition.
Series:Methods in molecular medicine ; 92.
Subjects:
Table of Contents:
  • Optimizing PCR for clinical diagnosis
  • Current and emerging techniques for diagnostic mutation detection : an overview of methods for mutation detection
  • Mutation scanning for the clinical laboratory : DHPLC
  • Mutation scanning for the clinical laboratory - protein truncation test
  • Mutation scanning for the clinical laboratory : automated fluorescent sequencing
  • Comparative sequence analysis
  • Gene dosage analysis by multiplex amplifiable probe hybridization
  • Prenatal detection of chromosome aneuploidy by quantitative fluorescence-PCR
  • Fragile X disease
  • Huntington's disease
  • Hematological applications : Hemoglobinopathies
  • Cystic fibrosis
  • Familial adenomatous polyposis
  • Multiple endocrine neoplasia types 1 and 2
  • Neurofibromatosis type 1 : a common familial cancer syndrome
  • Duchenne and Becker muscular dystrophy
  • Spinal muscular atrophy
  • Quality management in molecular genetics
  • Regulation of genetic testing in clinical practice