Molecular biology of B cells /
| Other Authors: | , , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Amsterdam ; Boston :
Elsevier,
2004.
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| Subjects: |
Table of Contents:
- Human immunoglobulin heavy chains locus
- Immunoglobulin heavy chain genes of mouse
- Immunoglobulin K genes of human and mouse
- Immunoglobulin lambda (IGL) genes of human and mouse
- The mechanism of V(D) J recombination
- Transcription of immunoglobulin genes
- Early B cell development to a mature, antigen-sensitive cell
- Allelic exclusion, isotypic exclusion and the developmental regulation of V(D)J recombination
- The development of human B lymphocytes
- Development and function of B cell subsets
- Structure and function of B cells antigen receptor complexes
- Regulation of antigen receptor signaling by the co-receptors, CD19 and CD22
- The dynamic structure of antibody responses
- Dynamics of B cell migration to and within secondary lymphoid organs
- Characteristics of mucosal B cells with emphasis on the human secretory immune system
- The cellular basis of B cell memory
- Immunoglobulin assembly and secretion
- Fc and complement responses
- Regulation of class switch recombination
- Molecular mechanism of class switch recombination
- Molecular mechanism of hypermutation
- Selection during antigen-driven B cell immune responses : the basis for high affinity antibody
- Diverse forms of immunoglobulin genes in lower vertebrates
- Immunoglobulin genes and generation of antibody repertoires in higher vertebrates : a key role for GALT
- The zebrafish immune system
- The origin of V(D)J diversification
- Antibody structure and recognition of antigen
- Monoclonal antibodies from display libraries
- Humanization of monoclonal antibodies
- Human monoclonal antibodies from translocus mice