Molecular cancer therapeutics : strategies for drug discovery and development /
| Other Authors: | |
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| Format: | Book |
| Language: | English |
| Published: |
Hoboken, N.J. :
Wiley-Liss,
[2004]
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| Subjects: |
Table of Contents:
- Molecular cancer therapeutics : will the promise be fulfilled?
- Cancer genetics and drug target selection
- RNA interference in mammals : journey to the center of human disease
- Applications and issues for tissue arrays in target and drug discovery
- Protein transduction strategies for target and mechanism validation
- Drug screening : assay development issues
- Gene microarray technologies for cancer drug discovery and development
- Transgenic mouse models of cancer
- Transgenic versus xenograft mouse models of cancer : utility and issues
- Pharmacodynamic assays in cancer drug discovery : from preclinical validation to clinical trial monitoring
- Pharmacokinetic and toxicology issues in cancer drug discovery and development
- Clinical development issues
- Intellectual property and commercialization issues in drug discovery