DNA repair in cancer therapy /
| Other Authors: | , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Totowa, N.J. :
Humana Press,
[2004]
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| Series: | Cancer drug discovery and development.
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| Subjects: |
Table of Contents:
- Clinical resistance to alkylators : status and perspective
- Role of nonhomologous end-joining and recombinational DNA repair in resistance to nitrogen mustard and DNA crosslinking agents
- Repair of DNA interstrand crosslinks produced by cancer chemotherapeutic drugs
- Chemosensitization to platinum-based anticancer drugs : current trends and future prospects
- Regulation of DNA repair and apoptosis by p53 and its impact on alkylating drug resistance of tumor cells
- Stress-activated signal transduction pathways in DNA damage response : implications for repair, arrest, and therapeutic interventions
- Overcoming resistance to alkylating agents by inhibitors of O⁶-alkylguanine-DNA alkyltransferase
- Cellular protection against the antitumor drug bleomycin
- Potential role of PARP inhibitors in cancer treatment and cell death
- Relationship among DNA repair genes, cellular radiosensitivity, and the response of tumors and normal tissues to radiotherapy
- Strand-break repair and radiation resistance
- V(D)J recombination and DNA double-strand-break repair : from immune deficiency to tumorigenesis
- Inherited disorders of genomic instability and cancer susceptibility
- Role of BRCA1 and BRCA2 in DNA repair and potential impact on therapeutics
- Genetic variations in DNA repair : their implications in human cancer risk, prevention, and therapy