Basic biology and clinical impact of immunosenescence /

Bibliographic Details
Other Authors: Pawelec, G. (Graham)
Format: Book
Language:English
Published: Amsterdam ; Boston : Elsevier, 2003.
Series:Advances in cell aging and gerontology. v. 13.
Subjects:
Table of Contents:
  • The OCTO and NONA immune longitudinal studies : a review of 11 years studies of Swedish very old humans
  • Immune measures which predict 9-year survival in an elderly population sample
  • Immunological and immunogenetic markers of successful and unsuccessful ageing
  • Developmental aspects of the thymus in aging
  • Effective immunity during late life ; a possible role for the thymus
  • Alterations in signal transduction in T lymphocytes and neutrophils with ageing
  • CD28 downregulation and expression of NK-associated receptors on T cells in aging and situations of chronic activation of the immune system
  • Characterisation of NK cells in the elderly
  • T cell ageing and immune surveillance
  • A road to ruins : an insight into immunosenescence
  • Genetic damage and ageing T cells
  • Role of DNA-dependent protein kinase (DNA-PK), a protein with multiple intracellular functions, in cells of the ageing immune system
  • Linker histone H1o gene expression during ageing and after the effect of histone deacetylase inhibitors in human diploid fibroblasts and T lymphocytes
  • Zinc and the immune system of elderly
  • Altered zinc binding by metallothioneins in immune-neuroendocrine senescence : a viscious circle between metallothioneins and chaperones?
  • T cell exhaustion and ageing : is replicative senescence relevant?
  • Cultured T cell clones as models for immunosenescence