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Proteases and their inhibitors in cancer metastasis /

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Bibliographic Details
Uniform Title:Proteases and their inhibitors in cancer metastasis (Print)
Other Authors: Foidart, Jean-Michel, 1949-, Muschel, Ruth J.
Format: Book
Language:English
Published: Dordrecht ; Boston : Kluwer Academic Publishers, [2002]
Series:Cancer metastasis (Series) ; v. 4.
Subjects:
Neoplasm Metastasis.
Protease Inhibitors.
Peptide Hydrolases.
Table of Contents:
  • Molecular biology of the plasminogen system : the delicate balance between tissue healing and tissue destruction
  • Role of serine proteases and their inhibitors in tumor growth and angiogenesis
  • The gelatinases, MMP-2 and MMP-9-implications for invasion and metastasis
  • The collagenases : novel roles for matrix metalloproteinases (MMPs) in invasion and metastasis
  • Stromelysin-3, a particular member of the matrix metalloproteinase family
  • Membrane-type matrix metalloproteinases
  • 3D structure and drug design
  • Transcriptional control of proteases
  • Tissue inhibitors of metalloproteinases in cancer
  • Clinical aspects of matrix metalloproteinases
  • Tissue models to study tumor-stroma interactions
  • Mammalian heparanase : molecular properties inhibition and involvement in tumor metastasis and angiogenesis