http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
xiii, 509 pages : illustrations ; 26 cm.
Clinical overview of uveal melanoma : introduction to tumors of the eye -- Clinical overview : retinoblastoma -- Epidemiology of retinoblastoma -- Genetics of uveal melanoma : chromosomal rearrangements and the identification of genes involved in tumorigenesis -- Structural alterations and gene expression in the pathogenesis of uveal melanoma -- A cascade of genomic changes leads to retinoblastoma -- The role of the retinoblastoma protein in health, malignancy, and the pathogenesis of retinoblastoma -- Biochemical pathways : differential gene expression and cellular pathways determining tumor phenotype comparison of uveal melanocytes and uveal melanoma cells in vitro -- p53 and the molecular regulation of cell fate in retinoblastoma -- Immunology of uveal melanoma : immunosuppressive factors and the basis for immunotherapy -- Models of uveal melanoma : characterization of transgenic mice and other animal models for melanoma -- Using retinoblastoma models to develop new treatment : vitamin D analogues -- Therapy of uveal melanoma : methods and risk factors associated with treatment -- The treatment of retinoblastoma -- Clinical trials in uveal melanoma : patient characteristics and the treatment of intraocular tumors -- Clinical trials in retinoblastoma -- Pathology of uveal melanoma : histological parameters and patient prognosis -- Retinoblastoma : pathology and prognosis -- Molecular genetics of retinoblastoma -- genetically engineered mouse models of retinoblastoma -- Treatment of extraocular retinoblastoma
edited by Daniel M. Albert, Arthur Polans.
Includes bibliographical references and index.