Mucus hypersecretion in respiratory disease /

Bibliographic Details
Uniform Title:Mucus hypersecretion in respiratory disease (Online)
Corporate Author: Novartis Foundation
Other Authors: Chadwick, Derek, Goode, Jamie
Format: eBook
Language:English
Published: Chichester, West Sussex, England ; Hoboken, NJ, USA : John Wiley & Sons, LTD, 2002.
Series:Novartis Foundation symposium ; 248.
Subjects:
Online Access:Mucus hypersecretion in respiratory disease (Online)
Table of Contents:
  • Epidemiological studies in mucus hypersecretion
  • Post-secretory fate of host defence components in mucus
  • Mechanisms of submucosal gland morphogenesis in the airway
  • Mucin-producing elements and inflammatory cells
  • Respiratory tract mucins : structure and expression patterns
  • Development and validation of a lectin-based assay for the quantitation of rat respiratory mucin
  • Regulation of mucin secretion from in vitro cellular models
  • Oscillations of pH inside the secretory granule control the gain of Ca²⁺ release for signal transduction in goblet cells exocytosis
  • A calcium-activated chloride channel blocker inhibits goblet cell metaplasis and mucus overproduction
  • Mechanisms by which Gram-positive bacteria and tobacco smoke stimulate mucin induction through the epidermal growth factor receptor
  • Non-allergic models of mucous cell metaplasia and mucus hypersecretion in rat nasal and pulmonary airways
  • Cytokine regulation of mucus production in a model of allergic asthma
  • The role of apoptotic regulators in metaplastic mucous cells
  • Current and future therapies for airway mucus hypersecretion
  • Clinical evaluation of new therapies for treatment of mucus hypersecretion in respiratory diseases.