TOR, target of rapamycin /

Bibliographic Details
Other Authors: Thomas, G. (George), Sabatini, D. M. (David M.), Hall, Michael N.
Format: Book
Language:English
Published: Berlin ; New York : Springer, 2004.
Series:Current topics in microbiology and immunology. 279.
Subjects:
Table of Contents:
  • TOR : the first ten years
  • The role of phosphatases in TOR signaling in yeast
  • Yeast TOR signaling : a mechanism for metabolic regulation
  • Nutrient signaling through TOR kinases controls gene expression and cellular differentiation in fungi
  • Autophagy in yeast : a TOR-mediated response to nutrient starvation
  • The fission yeast TOR proteins and the rapamycin response : an unexpected tale
  • Plant growth and the TOR pathway
  • TOR action in mammalian cells and in Caenorhabditis elegans
  • Genetic analysis of TOR signaling in Drosophilia
  • Interplay between growth factor and nutrient signaling : lessons from Drosophilia TOR
  • mTOR signaling to translation
  • Modulation of the protein kinase activity of mTOR
  • Role of mTOR signaling in the control of translation initiation and elongation by nutrients
  • Novel regulatory mechanisms of mTOR signaling
  • Raptor and mTOR : subunits of a nutrient-sensitive complex
  • Kinase activities associated with mTOR
  • mTOR : a mediator of intracellular homeostasis
  • mTOR as a positive regulator of tumor cell responses to hypoxia
  • Retroviral oncogenes and TOR
  • mTOR as a target for cancer therapy