Protein-ligand interactions : from molecular recognition to drug design /
| Other Authors: | , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Weinheim :
Wiley-VCH,
2003.
|
| Series: | Methods and principles in medicinal chemistry ;
v.19. |
| Subjects: |
Table of Contents:
- Prediction of non-bonded interactions in drug design
- Introduction to molecular recognition models
- Experimental approaches to determine the thermodynamics of protein-ligand interactions
- Biophore concept
- Receptor-ligand interaction
- Hydrogen bonds in protein-ligand complexes
- Principles of enzyme-inhibitor design
- Tailoring protein scaffolds for ligand recognition
- Small molecule screening of chemical microarrays