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An introduction to toxicogenomics /

Bibliographic Details
Other Authors: Burczynski, Michael E.
Format: Book
Language:English
Published: Boca Raton, Fla. : CRC Press, [2003]
Subjects:
Genomics.
Proteomics.
Gene Expression.
Table of Contents:
  • Preparation and utilization of microarrays
  • Comparative studies using cDNA vs. oligonucletide arrays
  • Quality control of expression profiling data
  • An introduction to cluster analysis
  • Transcriptional profiling in toxicology
  • Microarrays in drug metabolism and toxicology : rat liver responses to prototypical CYP inducers
  • Characterization of hepatocytes and their use as a model system in toxicogenomics
  • Molecular signatures of dioxin toxicity
  • Toxicogenomic dissection of the antioxidant response
  • An overview of mechanistic toxicogenomic studies
  • Gene expression profile databases in toxicity testing
  • Predictive toxicogenomics
  • Unsupervised hierarchical clustering of toxicants
  • Toxicogenomic analysis in clinical pharmacogenomic studies
  • The future of toxicogenomics