The sodium-hydrogen exchanger : from molecule to its role in disease /

Bibliographic Details
Other Authors: Karmazyn, M. (Morris), 1950-, Avkiran, M. (Metin), Fliegel, Larry, 1956-
Format: Book
Language:English
Published: Boston : Kluwer Academic Publishers, [2003]
Subjects:
Table of Contents:
  • Regulation of intracellular pH in mammalian cells
  • Molecular and functional diversity of mammalian Na⁺/H⁺ exchangers
  • Two functional regulatory factors of the Na⁺/H⁺ exchangers
  • The proton and CHP
  • Regulation of expression of the Na⁺/H⁺ exchanger in the myocardium and other tissues
  • Na-H exchange function in colonic epithelial cells
  • NhaA Na⁺/H⁺ antiporter. Structure, mechanism and function in homestasis of Na⁺ and pH
  • The use of transgenic animal models to study Na⁺ /H⁺ exchange
  • pH-regulatory mechanisms in the mammalian oocyte and early embryo
  • Na⁺/H⁺ exchanger activation by myocardial stretch
  • The paradoxical role of Na⁺/H⁺ exchanger in the diabetic heart
  • Role of Na-H exchanger in vascular remodelling in diabetes
  • The potential role of the Na⁺/H⁺ exchanger in ischemia/reperfusion injury of the central nervous system
  • Receptor-mediated regulation of the cardiac sarcolemmal Na⁺/H⁺ exchanger
  • Role of the NHE-1 in cardiac hypertrophy and heart failure
  • Mechanisms underlying NHE-1 involvement in myocardial ischemic and reperfusion injury
  • Chemistry of NHE inhibitors
  • Development of NHE inhibitors for cardiovascular therapeutics
  • Cardiac protection by NHE inhibitors
  • NHE-1 inhibitors : potential application in cardiac surgery
  • NHE-1inhibition : a potential new treatment for resuscitation from cardiac arrest