http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
xxxii, 318 pages : illustrations ; 25 cm.
Regulation of intracellular pH in mammalian cells -- Molecular and functional diversity of mammalian Na⁺/H⁺ exchangers -- Two functional regulatory factors of the Na⁺/H⁺ exchangers -- The proton and CHP -- Regulation of expression of the Na⁺/H⁺ exchanger in the myocardium and other tissues -- Na-H exchange function in colonic epithelial cells -- NhaA Na⁺/H⁺ antiporter. Structure, mechanism and function in homestasis of Na⁺ and pH -- The use of transgenic animal models to study Na⁺ /H⁺ exchange -- pH-regulatory mechanisms in the mammalian oocyte and early embryo -- Na⁺/H⁺ exchanger activation by myocardial stretch -- The paradoxical role of Na⁺/H⁺ exchanger in the diabetic heart -- Role of Na-H exchanger in vascular remodelling in diabetes -- The potential role of the Na⁺/H⁺ exchanger in ischemia/reperfusion injury of the central nervous system -- Receptor-mediated regulation of the cardiac sarcolemmal Na⁺/H⁺ exchanger -- Role of the NHE-1 in cardiac hypertrophy and heart failure -- Mechanisms underlying NHE-1 involvement in myocardial ischemic and reperfusion injury -- Chemistry of NHE inhibitors -- Development of NHE inhibitors for cardiovascular therapeutics -- Cardiac protection by NHE inhibitors -- NHE-1 inhibitors : potential application in cardiac surgery -- NHE-1inhibition : a potential new treatment for resuscitation from cardiac arrest
edited by Morris Karmazyn, Metin Avkiran, Larry Fliegel.
Includes bibliographical references and index.