Ion channels : from atomic resolution physiology to functional genomics /

Bibliographic Details
Corporate Author: Novartis Foundation
Other Authors: Bock, Gregory, Goode, Jamie
Format: Book
Language:English
Published: New York : Chichester : Wiley, 2002.
Series:Novartis Foundation symposium ; 245.
Subjects:
Table of Contents:
  • Introduction : stretching the envelope in structure-function studies of ion channels
  • Structure of the acetylcholine-gated channel
  • The 2.7 A structure of AChBP, homologue of the ligand-binding domain of the nicotinic acetylcholine receptor
  • The architecture of a water-selective pore in the lipid bilayer visualized by electron crystallography in vitreous ice
  • The structure of GlpF, a glycerol conducting channel
  • Water in ion channels and pores : simulation studies
  • What can be deduced about the structure of Shaker from available data? -Permeation energetics in a model potassium channel
  • The beta subunit of Kv1 channels : voltage-gated enzyme or safety switch?
  • EPR approaches to ion channel structure and function
  • From structure to channel physiology
  • Excitability is mediated by the T1 domain of the voltage-gated potassium channel
  • Structural organization of the voltage sensor in voltage-dependent potassium channels
  • Electron diffraction of a bacterial CIC-type chloride channel
  • A protein chemical approach to channel structure and function : the proton channel of the vacuolar H⁺-ATPase
  • Acetylcholine receptors, between closed and open
  • Functional genomics of ionotropic acetylcholine receptors in Caenorhabditis elegans and Drosophila melanogaster