Tissue oxygenation in acute medicine /

Bibliographic Details
Other Authors: Sibbald, William J., Messmer, K. (Konrad), Fink, M. P. (Mitchell P.), 1948-
Format: Book
Language:English
Published: New York : Springer, [2002]
Series:Update in intensive care and emergency medicine ; v. 33.
Subjects:
Table of Contents:
  • Role of cardiorespiratory system in delivering oxygen
  • Intraorgan heterogeneity of blood flow, oxygen consumption and tissue oxygenation
  • Oxygen distribution and consumption by the microcirculation and the determinants of tissue survival
  • Oxygen signaling cascades in mammalian cells
  • Hypoxic hypoxia
  • Circulatory hypoxia
  • Anemic hypoxia
  • Cytopathic hypoxia : mitochondrial dysfunction as a potential mechanism contributing to organ failure in sepsis
  • Poly (ADP-ribose) synthetase activation in circulatory shock
  • Cellular responses to hypoxia : possible relevance to mulitiple organ failure in critical illness?
  • The mitochondrial permeability transition
  • The available clinical tools - oxygen-derived variables, lactate, and pHi
  • Microcirculatory flows, microcirculatory responsiveness, microcirculatory and regional ( arteriolar/venular) O₂ saturations
  • Monitoring the systemic circulation in sepsis with microelectrodes
  • Oxygen electrodes, optode microsensing, near-infrared spectroscopy, spectrophotometry
  • The optimal and critical hemoglobin in health and acute illness
  • Hemoglobin-based artificial oxygen carriers (HBOC) : classification and historical overview
  • Hemoglobin solutions : effects on tissue oxygenation
  • Effect of diaspirin crosslinked hemoglobin on systemic and regional blood circulation
  • Blood substitutes - effects on the microcirculation
  • Perfluorocarbons as oxygen carriers
  • Serum-free hemoglobin increases tumor necrosis factor synthesis and lipopolysaccharide lethality
  • Enhancement of tissue oxygenation by intracellular introduction of inositol hexaphosphate by flow electroporation of red blood cells