Viral vectors for gene therapy : methods and protocols /

Bibliographic Details
Other Authors: Machida, Curtis A.
Format: Book
Language:English
Published: Totowa, N.J. : Humana Press, [2003]
Series:Methods in molecular medicine ; 76.
Subjects:
Table of Contents:
  • Use of the herpes simplex viral genome to construct gene therapy vectors
  • Construction of mutiply disabled herpes simplex viral vectors for gene delivery to the nervous system
  • Improved HSV-1 amplicon packaging system using ICP27-deleted, oversized HSV-1 BAC DNA
  • Herpes simplex amplicon vectors
  • Strategies to adapt adenoviral vectors for targeted delivery
  • Use of recombinant adenovirus for gene transfer into the rat brain : evaluation of gene transfer efficiency, toxicity, and inflammatory and immune reactions
  • Generation of adenovirus vectors devoid of all virus genes by recombination between inverted repeats
  • Packaging cell lines for generating replication-defective and gutted adenoviral vectors
  • Improving the transcriptional regulation of genes delivered by adenovirus vectors
  • Targeted integration by adeno-associated virus
  • Development and optimization of adeno-associated virus vector transfer into the central nervous system
  • A method for helper virus-free production of adeno-associated virus vectors
  • Recombinant adeno-associated viral vector types 4 and 5 : preparation and application for CNS gene transfer
  • Trans-splicing vectors expand the packaging limits of adeno-associated virus for gene therapy applications
  • Generation of retroviral packaging and producer cell lines for large-scale vector production with improved safety and titer
  • An ecdysone-inducible expression system for use with retroviruses
  • In vivo infection of mice by replication-competent MLV-based retroviral vectors
  • Development of simian retroviral vectors for gene delivery
  • Self-inactivating lentiviral vectors and a sensitive Cre-loxP reporter system
  • Lentiviral vectors for gene transfer to the central nervous system : application in lysosomal storage disease animal models
  • A highly efficient gene delivery system derived from feline immunodeficiency virus (FIV)
  • A multigene lentiviral vector system based on differential splicing
  • Production of Trans-lentiviral vector with predictable safety
  • Human immunodeficiency virus type 1-based vectors for gene delivery to human hematopoietic stem cells
  • Semliki forest viral vectors for gene transfer
  • Semliki forest virus (SFV) vectors in neurobiology and gene therapy
  • Semliki forest virus vectors for large -scale production of recombinant proteins
  • Development of foamy virus vectors
  • Poxviral/retroviral chimeric vectors allow cytoplasmic production of transducing defective retroviral particles