Gene therapy of cancer : translational approaches from preclinical studies to clinical implementation /

Bibliographic Details
Other Authors: Lattime, Edmund C., 1951-, Gerson, Stanton L.
Format: Book
Language:English
Published: London : Academic, 2002.
Edition:Second edition.
Subjects:
Table of Contents:
  • Retroviral vector design for cancer gene therapy
  • Noninfectious gene transfer and expression systems for cancer gene therapy
  • Parvovirus vectors for the gene therapy of cancer
  • Antibody-targeted gene therapy
  • Ribozymes in cancer gene therapy
  • The advent of lentiviral vectors : prospects for cancer therapy
  • Immunologic targets for the gene therapy of cancer
  • Development of epitope-specific immunotherapies for human malignancies and premalignant lesions expression mutated ras genes
  • Introduction to dendritic cells
  • DNA and dendritic cell-based genetic immunization against cancer
  • RNA-transfected dendritic cells as immunogens
  • In situ immune modulation using recombinant vaccinia virus vectors : preclinical studies to clinical implementation
  • The use of particle-mediated gene transfer for immunotherapy of cancer
  • Applications of gene transfer in the adoptive immunotherapy of cancer
  • Update on the use of genetically modified hematopoietic stem cells for cancer therapy
  • Clinical applications of tumor-suppressor gene therapy
  • Cancer gene therapy with tumor suppressor genes involved in cell-cycle control
  • Cancer gene therapy with the p53 tumor suppressor gene
  • Antisense downregulation of the apoptosis-related Bcl-2 and Bcl-xl proteins : a new approach to cancer therapy
  • Gene therapy for chronic myelogenous leukemia
  • Transfer of drug-resistance genes into hematopoietic progenitors
  • Multidrug-resistance gene therapy in hematopoietic cell transplantation
  • Development and spplication of an engineered dihydrofolate reductase and cytidine-deaminase-based fusion genes in myeloprotection-based gene therapy strategies
  • Protection from antifolate toxicity by expression of drug-resistant dihydrofolate reductase
  • A genomic approach to the treatment of breast cancer
  • Antiangiogenic gene therapy
  • VEGF-targeted antiangiogenic gene therapy
  • Strategies for combining gene therapy with ionizing radiation to improve antitumor efficacy
  • Virotherapy with replication-selective oncolytic adenoviruses : a novel therapeutic platform for cancer
  • E 1 A cancer gene therapy
  • Preemptive and therapeutic uses of suicide genes for cancer and leukemia
  • Treatment of mesothelioma using adenoviral-mediated delivery of herpes simplex virus thymidine kinase gene in combination with ganciclovir
  • The use of suicide gene therapy for the treatment of malignancies of the brain
  • Case study of combined gene and radiation therapy as an approach in the treatment of cancer