Combinatorial library : methods and protocols /
| Other Authors: | |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Totowa, N.J. :
Humana Press,
[2002]
|
| Series: | Methods in molecular biology (Clifton, N.J.) ;
v. 201. |
| Subjects: |
Table of Contents:
- Pt. I. Library synthesis and quality control
- Using a noncovalent protection strategy to enhance solid-phase synthesis
- Quality control of solid-phase synthesis by mass spectrometry
- Preparation of encoded combinatorial libraries for drug discovery
- Simple tools for manual parallel solid phase synthesis
- Cleavage of compounds from solid phase by gaseous reagents
- Synthesis of DNA-binding polyamides : robust solid-phase methods for coupling heterocyclic aromatic amino acids
- The preparation of phenyl-stilbene derivatives using the safety catch linker
- Host-guest chemistry : combinatorial receptors
- Automated structure verification of small molecules libraries using 1D and 2D NMR techniques
- Rapid liquid-phase combinatorial synthesis of heterocyclic libraries
- Soluble polymer-supported methods for combinatorial and organic synthesis
- Analytical methods for optimization and quality control of combinatorial synthesis
- Pt. II. Library purification and screening
- Resolving racemic mixtures using parallel combinatorial libraries
- Ligand libraries for the extraction of metal ions : dynamic combinatorial and high-throughout screening methods
- Automated liquid-liquid extraction and ion-exchange solid-phase extraction for initial purification
- On-bead and solution screening approaches for genomically derived targets : discovery of surrogate ligands and substrates using combinatorial chemistry libraries
- Pt. III. Computational library design
- Design of virtual combinatorial libraries
- Approaches to library design for combinatorial chemistry
- Reagent-based and product-based computational strategies in library design
- Designing combinatorial libraries for efficient screening
- Application of neural networks to large dataset QSAR, virtual screening, and library design