Clinical drug trials and tribulations /

Bibliographic Details
Other Authors: Cato, Allen E., 1939-, Sutton, Lynda, 1956-, Cato, Allen, 1963-
Format: Book
Language:English
Published: New York : Marcel Dekker, [2002]
Edition:Second edition, revised and expanded.
Series:Drugs and the pharmaceutical sciences ; v. 120.
Subjects:
Table of Contents:
  • Current challenges and future directions of drug development
  • Preclinical drug discovery and development
  • The IND process for new drug products
  • Performance and interpretation of laboratory tests
  • Issues in endpoint selection
  • Dix, cent, mille : proof of principle with $10 million, 100 patients, and 1000 days
  • Clinical trials in pediatrics : dilemmas of clinical drug trials in pediatric populations
  • Electronic capture of clinical trial information
  • Providing patient access to promising investigational drugs
  • Issues in the review of clinical drug trials by IRBs
  • Personal care and randomized clinical trials : understanding the ethical conflicts
  • Informed consent in clinical trials : emerging issues
  • Orphan drug development : David and Goliath
  • Singel-event adverse drug reactions : tribulations in ascribing causality
  • How to deal with a sudden, unexpected death in clinical studies
  • Clinical trial material - the fuel for clinical research
  • The role of pharmacokinetics in drug development
  • Building an NDA/BLA
  • International planning of drug clinical trials
  • Uncertainty in drug development : approval success rates for new drugs
  • Contract clinical research : value to in-house drug development
  • Package inserts as viewed by the busy private practitioner
  • New directions in pharmaceutical promotion : regulatory concerns and contrivances
  • The campus researcher and industry : issues of intellectual property and technology transfer
  • Anatomy of drug withdrawals in the United States